Holmby Hills North is the portion north of Sunset that is east of Beverly Glen Boulevard and west of the city limits of Beverly Hills, with Greendale Drive and Brooklawn Drive as its northernmost streets. It is located within the Bel Air Beverly Crest Community Plan Area, though it is historically distinct from the neighborhoods of both Bel Air and Beverly Crest, as it was developed concurrently with Westwood. The northern section is served by the Holmby Hills Homeowners Association.

The Frederick R. Weisman Art Foundation, an art gallery named after Frederick R. Weisman, is located on 265 North Carolwood Street. It includes works by many noted artists, including impressionists, post impressionist, surrealist, and many more, up through today. The villa was designed by Gordon B. Kaufmann in the late 1920s and exhibits the craftsmanship characteristics of that period, including hand-painted ceilings, stucco details, and wood-inlaid floors.

Holmby Hills North noteworthy former residents and estates include; Claudette Colbert at 615 N Faring Rd. Colbert commissioned Lloyd Wright to design this house in 1935, when there was only one other house on the street. Fanny Brice at 312 N Faring Rd. Is now the The Faring Estate by renowned architect Oscar Shamamian with two guest houses, one an original by architect John Elgin Woolf., Walt Disney at 355 N Carolwood Dr, Gregory Peck at 375 N Carolwood Dr and 111 N Mapleton Dr by Paul Williams, 1936 on over 1.3 acres of land.

Holmby Hills North is home to De Neve Square Park and Harvard Westlake School.